医学翻译

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Figure 4. IVIg renders DCs refractory to LPS-mediated maturation. (A) DCs were generated as described in “Materials and methods.” At day 5, immature DCs were treated

with IVIg (0.15 mM) for 12 hours followed by stimulation with LPS (1 g/mL) (middle row) or were treated with LPS alone (top row) for 48 hours. In control experiments, cells

were treated with HSA as an irrelevant protein for 12 hours followed by stimulation with LPS (1 g/mLbottom row). Percentages of cells positive for the indicated markers are

depicted in upper right corners. Dark histograms represent isotype control. (B) In a second set of experiments, immature DCs were stimulated with LPS (1 g/mL) for 3 hours

followed by incubation with IVIg (bottom row) or without IVIg (top row) for 48 hours. Percentages of cells positive for the indicated markers are depicted in upper right corners,

and MFI is indicated in parentheses. Results shown are representative of 4 independent experiments from different donors. (C) Effect of different sources of IVIg on

LPS-mediated maturation of dendritic cells. Monocyte-derived DCs were stimulated with LPS (1 g/mL) for 3 hours followed by incubation with Gammagard, Endobuline,

Intraglobin, and Sandoglobulin (0.15 mM) for 48 hours. The percentage down-regulation of MFI of surface molecules on DCs following IVIg treatment is shown. LPS-treated

DCs represented 100% expression. Data are represented as means and standard deviations calculated from 2 independent experiments from different donors. 图4 。丙种球蛋白，使区议会的难治内毒素介导的成熟程度。 （一）所产生的区议会中所述的“材料与方法”在第5天，不成熟的区议会的治疗

与免疫球蛋白（ 0.15毫米）为12小时，其次是刺激与LPS （ 1克/毫升） （中排）或治疗与LPS单（首行）为48小时。在控制实验，细胞

治疗与人血清白蛋白作为一个不相干的蛋白质为12小时，其次是刺激与LPS （ 1克/毫升底部一行） 。百分比的细胞呈阳性，显示的标记

描绘在右上角的角落。黑暗的直方图代表isotype控制。 （ b ）在第二组实验中，不成熟的区议会的刺激与LPS （ 1 g / ml ）作用3小时

其次是培育与免疫球蛋白（底部行）或无丙种球蛋白（首行）为48小时。百分比的细胞呈阳性，显示的标记是描绘在右上角的角落，

和MFI是表示，在括号中。结果表明，有代表性的4个独立的实验，从不同的捐助者。 （三）的影响，不同来源的丙种球蛋白对

内毒素介导的成熟的树突状细胞。单核细胞衍生的区议会的刺激与LPS （ 1克/毫升）为3个小时之后孵化与gammagard ， endobuline ，

intraglobin ， sandoglobulin （ 0.15毫米）为48小时。百分比下降的规管MFI的表面分子在DCS以下给予静脉注射免疫球蛋白治疗结果表明。内毒素治疗

区议会的代表100 ％的表达。数据派代表作为均值和标准差计算出来的2个独立的实验，从不同的捐助者。

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